Cytology is the study of cells under a microscope. We collect a small sample, often from a lump, the skin, the ears or fluid, and examine it to look for infection, inflammation or abnormal cells.

Samples are often taken with a fine needle and usually don't require sedation. Many cytologies can be read here in the hospital, so we can start treatment sooner, and we can send samples to a pathologist when a second look is needed.

Common Reasons Your Vet May Recommend Cytology

Cytology is a quick, minimally invasive way to learn more about a problem without surgery, and it's useful for both dogs and cats. Results help your vet decide on the right next step, whether that's medication, monitoring or removing a mass. Your vet may suggest cytology when your dog or cat has:

  • A new lump or bump, or a lump that has changed in size or feel
  • Itchy, red or flaky skin that could involve bacteria or yeast
  • Ear discharge, odor or head shaking
  • Swollen lymph nodes
  • Fluid buildup in the chest, abdomen or a joint
  • Sores, scabs or areas of hair loss that aren't healing or keep coming back

What to Expect During a Fine Needle Aspirate

A fine needle aspirate is one of the most common ways to collect cells. Your vet places a small needle into the lump or area of concern and draws out a tiny sample. It feels similar to a vaccine, and most pets tolerate it calmly while gently held. Sedation is occasionally used for sensitive areas or anxious pets.

For skin and ear samples, your vet may instead use tape, a swab or a gentle scraping. The cells are spread on a slide, stained and examined under the microscope. Cytology doesn't always give a final answer. If results are unclear, your vet may recommend a biopsy, which looks at a larger piece of tissue.

Questions about Cytologies?

Call us or book an appointment online, and our team will help you decide on the next step for your pet.

Cytologies: Frequently Asked Questions

Does a fine needle aspirate hurt my pet?
Most pets feel only a brief pinch, similar to a vaccine, and many barely react. The needle is small and the procedure takes just a moment. Your vet may use sedation for anxious pets or sensitive areas.
What is the difference between cytology and a biopsy?
Cytology looks at individual cells collected with a needle, swab or tape, and is quick and minimally invasive. A biopsy removes a piece of tissue so a pathologist can see how cells are arranged. A biopsy is sometimes needed for a definitive diagnosis.
Can cytology tell if a lump is cancer?
Cytology can often identify common benign lumps, such as fatty tumors, and may show cells that suggest cancer. Some masses don't release enough cells for a clear answer, so your vet may recommend a biopsy or pathologist review.
Should I have every new lump on my pet checked?
Yes, it's a good idea to have any new lump looked at, since you can't tell what it is by feel alone. Note when you found it and its size, and let your vet know if it grows, changes or bothers your pet.

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